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Decreasing Polypharmacy in Older Adults With Curable Cancers Trial
Sponsor: University of Rochester
Summary
This is a single-site cluster-randomized trial to assess efficacy and implementation outcomes of deprescribing interventions in 72 older adults with polypharmacy (PP) and curable cancers initiating chemotherapy. Oncologists (as the cluster) will enroll 6 patients each and will be randomized to either a pharmacist-led deprescribing intervention or patient education intervention. Initial focus groups with oncologists, nurses, pharmacists, primary care physicians, and patients will provide data for initial adaptations to the pharmacist-led intervention arm, and 8 patients will be enrolled as a pre-trial cohort to further refine and adapt the pharmacist-led intervention.
Official title: Decreasing Polypharmacy in Older Adults With Curable Cancers: a Pilot Cluster-randomized Trial
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2022-06-14
Completion Date
2025-12-31
Last Updated
2026-08-19
Healthy Volunteers
No
Conditions
Interventions
Pharmacist-led deprescribing
A pharmacist recruited onto the study will review the patient's current medication list and develop a list of targeted recommendations for deprescribing using the 3-step potentially inappropriate medications identification method.
Patient education
Subjects receive a written pamphlet about deprescribing.
Locations (1)
University of Rochester
Rochester, New York, United States