Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT05046171
PHASE1/PHASE2

Decreasing Polypharmacy in Older Adults With Curable Cancers Trial

Sponsor: University of Rochester

View on ClinicalTrials.gov

Summary

This is a single-site cluster-randomized trial to assess efficacy and implementation outcomes of deprescribing interventions in 72 older adults with polypharmacy (PP) and curable cancers initiating chemotherapy. Oncologists (as the cluster) will enroll 6 patients each and will be randomized to either a pharmacist-led deprescribing intervention or patient education intervention. Initial focus groups with oncologists, nurses, pharmacists, primary care physicians, and patients will provide data for initial adaptations to the pharmacist-led intervention arm, and 8 patients will be enrolled as a pre-trial cohort to further refine and adapt the pharmacist-led intervention.

Official title: Decreasing Polypharmacy in Older Adults With Curable Cancers: a Pilot Cluster-randomized Trial

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2022-06-14

Completion Date

2025-12-31

Last Updated

2026-08-19

Healthy Volunteers

No

Conditions

Interventions

OTHER

Pharmacist-led deprescribing

A pharmacist recruited onto the study will review the patient's current medication list and develop a list of targeted recommendations for deprescribing using the 3-step potentially inappropriate medications identification method.

OTHER

Patient education

Subjects receive a written pamphlet about deprescribing.

Locations (1)

University of Rochester

Rochester, New York, United States