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ACTIVE NOT RECRUITING
NCT05047068

OCS Heart Perfusion Post-Approval Registry

Sponsor: TransMedics

View on ClinicalTrials.gov

Summary

The objective of this post-approval registry is to provide additional real-world evidence of the performance of the OCS Heart System to preserve DBD and DCD donor hearts.

Official title: OCS Heart Perfusion (OHP) Post-Approval Registry

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

350

Start Date

2021-09-13

Completion Date

2029-12

Last Updated

2025-10-30

Healthy Volunteers

No

Conditions

Interventions

DEVICE

OCS Heart System

The TransMedics® OCS Heart System is a portable system available for ex-vivo maintenance of a donor heart in a metabolically active and beating state. The OCS Heart System's innovative technology was designed to comprehensively overcome the historical limitations of cold storage. The OCS Heart System expands the utilization of donor hearts by enabling the use of donor hearts deemed unsuitable for procurement and transplantation at initial evaluation due to limitations of cold static cardioplegic preservation.

Locations (27)

Cedars Sinai

Los Angeles, California, United States

Stanford University

Palo Alto, California, United States

University of California San Francisco

San Francisco, California, United States

Yale New Haven Hospital

New Haven, Connecticut, United States

Mayo Clinic Florida

Jacksonville, Florida, United States

Tampa General Hospital

Tampa, Florida, United States

Emory University Hospital

Atlanta, Georgia, United States

Northwestern Medicine

Chicago, Illinois, United States

University of Kentucky

Lexington, Kentucky, United States

Tufts Medical Center

Boston, Massachusetts, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Brigham and Women's Hospital

Boston, Massachusetts, United States

University of Michigan

Ann Arbor, Michigan, United States

Minneapolis Heart Institute

Minneapolis, Minnesota, United States

University of Minnesota

Minneapolis, Minnesota, United States

Mayo Clinic Rochester

Rochester, Minnesota, United States

Columbia University Irving Medical Center/ New York Presbyterian Hospital

New York, New York, United States

Montefiore

The Bronx, New York, United States

Westchester Medical Center

Valhalla, New York, United States

Duke University

Durham, North Carolina, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Baylor Scott and White

Dallas, Texas, United States

Medical City Dallas

Dallas, Texas, United States

Methodist Hospital

San Antonio, Texas, United States

University of Washington Medical Center

Seattle, Washington, United States

Froedtert & the Medical College of Wisconsin

Milwaukee, Wisconsin, United States