Clinical Research Directory
Browse clinical research sites, groups, and studies.
GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma
Sponsor: Chinese Academy of Sciences
Summary
This study is to evaluate whether intraoperative fluorescence imaging targeting GPC3 can aid improve the surgical accuracy of hepatocellular carcinoma. The main purposes of this study include: ① To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the GPC-3 targeted fluorophore. ② To validate the safety and effectiveness of the designed GPC-3 targeted fluorophore for clinical application.
Official title: An Evaluation Study of GPC3 Targeted Fluorescence Imaging to Guide the Surgery of Hepatocellular Carcinoma
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2021-09-10
Completion Date
2026-12-31
Last Updated
2023-08-30
Healthy Volunteers
Yes
Conditions
Interventions
Anti-GPC3-IRDye800CW
Drug Injection: Anti-GPC3-IRDye800CW
Locations (2)
Zhuhai People's Hospital
Zhuhai, Guangdong, China
The Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, China