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COMPLETED
NCT05053932

Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Sickle Cell Anemia

Sponsor: Centre Hospitalier Intercommunal Creteil

View on ClinicalTrials.gov

Summary

The purpose of the present observational study is to remotely reevaluate the cohort of 67 sickle cell patients with transcranial Doppler-detected cerebral vasculopathy included in the national "Sickle Cell Transplant" protocol and whose 1- and 3-year results were published in JAMA (Journal of the American Medical Association) in 2019 and in BHJ in 2020.

Official title: Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Children With Sickle Cell Anemia ( DREPAGREFFE-2)

Key Details

Gender

All

Age Range

13 Years - Any

Study Type

OBSERVATIONAL

Enrollment

67

Start Date

2022-10-07

Completion Date

2025-01-31

Last Updated

2026-06-15

Healthy Volunteers

No

Interventions

OTHER

blood collection

blood collection

Locations (14)

Hôpital Robert Debré AP-HP

Paris, IDF, France

Groupe hospitalier Pellegrin

Bordeaux, France

Centre Hospitalier Intercommunal de Créteil

Créteil, France

Hôpital Henri Monr - APHP

Créteil, France

CHU de la Guadeloupe

La Guadeloupe, France

Hôpital Bicêtre AP-HP

Le Kremlin-Bicêtre, France

IHOPe

Lyon, France

CHU de Lyon

Lyon, France

Hôpital de la Timone

Marseille, France

CHU de Montpellier

Montpellier, France

Hôpital Necker - AP-HP

Paris, France

CH de Pau

Pau, France

CHU de Rennes

Rennes, France

Hôpital Hautepierre

Strasbourg, France