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Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Sickle Cell Anemia
Sponsor: Centre Hospitalier Intercommunal Creteil
Summary
The purpose of the present observational study is to remotely reevaluate the cohort of 67 sickle cell patients with transcranial Doppler-detected cerebral vasculopathy included in the national "Sickle Cell Transplant" protocol and whose 1- and 3-year results were published in JAMA (Journal of the American Medical Association) in 2019 and in BHJ in 2020.
Official title: Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Children With Sickle Cell Anemia ( DREPAGREFFE-2)
Key Details
Gender
All
Age Range
13 Years - Any
Study Type
OBSERVATIONAL
Enrollment
67
Start Date
2022-10-07
Completion Date
2025-01-31
Last Updated
2026-06-15
Healthy Volunteers
No
Interventions
blood collection
blood collection
Locations (14)
Hôpital Robert Debré AP-HP
Paris, IDF, France
Groupe hospitalier Pellegrin
Bordeaux, France
Centre Hospitalier Intercommunal de Créteil
Créteil, France
Hôpital Henri Monr - APHP
Créteil, France
CHU de la Guadeloupe
La Guadeloupe, France
Hôpital Bicêtre AP-HP
Le Kremlin-Bicêtre, France
IHOPe
Lyon, France
CHU de Lyon
Lyon, France
Hôpital de la Timone
Marseille, France
CHU de Montpellier
Montpellier, France
Hôpital Necker - AP-HP
Paris, France
CH de Pau
Pau, France
CHU de Rennes
Rennes, France
Hôpital Hautepierre
Strasbourg, France