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RECRUITING
NCT05053945

Helicobacter Pylori, Atrophic Gastritis and Intestinal Metaplasia Registry and Prospective Study

Sponsor: Chinese University of Hong Kong

View on ClinicalTrials.gov

Summary

Since much is unknown about factors that lead to progression of the pre-neoplastic lesions and cancer. In addition, there is ongoing debate on the optimal surveillance intervals and techniques. To solve these important clinical questions, the establishment of a registry for a longitudinal study is planned.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

260

Start Date

2020-05-15

Completion Date

2025-12-31

Last Updated

2024-08-29

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Esophagogastroduodenoscopy

To set up a prospective study and registry (HAR-P) for patients with H. pylori infection, atrophic gastritis or intestinal metaplasia to evaluate their clinical features and outcomes. The objectives include: 1. Assess the short- and long-term patient outcomes of H. pylori patients 2. Characterize factors involved in the progression or regression of pre-neoplastic lesions, namely atrophic gastritis and intestinal metaplasia 3. Gather information for a better understanding on the efficacy and role of surveillance 4. Potential for the development of new screening/surveillance strategies and tools for better risk stratification of patients 5. Establish a biobank for H. pylori, atrophic gastritis and intestinal metaplasia patients

Locations (2)

Prince of Wales Hospital

Hong Kong, Hong Kong

S.H. Ho Centre for Digestive Health, Prince of Wales Hospital

Hong Kong, Hong Kong