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Effects of a Polyphenol-rich Cranberry Extract on Cardiometabolic and Neurocognitive Health
Sponsor: Laval University
Summary
The objective of this double-blind, parallel, randomized placebo-controlled clinical trial is to evaluate the effects of consumption of polyphenol-rich cranberry extract standardized in PACs (36 mg PACs/capsule) on cardiometabolic and neurocognitive health in women and men presenting abdominal obesity over an 8-week intervention period. The study will be conducted at Quebec Heart and Lung Institute - Laval University. The study will involve a total of 60 adult men and women presenting abdominal obesity. Included participants will be randomly assigned to the consumption of a cranberry extract or a placebo at a rate of one capsule per day for 8 weeks (56 days). The main outcomes are changes in metabolic profile, neurocognitive performance as well as brain structure and function following polyphenol-rich cranberry extract standardized in PACs compared with the placebo.
Official title: Effects of a Polyphenol-rich Cranberry Extract on Cardiometabolic and Neurocognitive Health in Individuals With Abdominal Obesity: a Double-blind Randomized Controlled Trial
Key Details
Gender
All
Age Range
30 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
49
Start Date
2021-10-21
Completion Date
2025-01-09
Last Updated
2026-08-26
Healthy Volunteers
Yes
Conditions
Interventions
Polyphenol-rich cranberry extract supplement standardized in proanthocyanidins
Participants will be randomly assigned to the consumption of one capsule of Polyphenol-rich cranberry extract standardized in PACs.
Placebo supplement
Participants will be randomly assigned to the consumption of one capsule of placebo per day for 56 consecutive days.
Locations (1)
Quebec Heart and Lung Institute - Laval University
Québec, Quebec, Canada