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The Roles of Gut Microbiome in UTI Susceptible Women
Sponsor: University of Florida
Summary
Clinical trials on cranberry juice and UTI prevention yielded both positive and negative results for unknown reason. Gut microbiome in women affect the absorption and metabolism of cranberry bioactives. The variation of gut microbiome is a probable mechanism for metabolic polymorphisms and disparity in UTI prevention in women.
Official title: Investigate the Roles of Gut Microbiome in the Differential Responses of UTI Susceptible Women to Cranberry Juice Intake
Key Details
Gender
FEMALE
Age Range
21 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2021-10-18
Completion Date
2026-08
Last Updated
2025-09-05
Healthy Volunteers
Yes
Conditions
Interventions
Cranberry juice
The responders and non-responders will drink 20-30 oz of (590-885 mL) 27% cranberry juice daily for 3 weeks.
Apple juice
The participants will drink apple juice with matching sugar content and calories for 3 weeks
Locations (1)
University of Florida
Gainesville, Florida, United States