Clinical Research Directory
Browse clinical research sites, groups, and studies.
Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness
Sponsor: Yale University
Summary
Millions of Americans suffer from high blood pressure, diabetes, strokes and motor vehicle accidents due to ineffective treatment of obstructive sleep apnea (OSA). Our preliminary data suggest that physiological causes of OSA such as easy arousability (low arousal threshold) or unstable breathing control (high loop gain) may influence effectiveness of OSA's most common treatment, continuous positive airway pressure (CPAP). The NICE-PAP study will examine how the physiologic traits that cause OSA in each individual impact CPAP effectiveness and can lead to personalized OSA treatments that improve patient lives.
Official title: Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness: NICEPAP Study Prospective Cohort
Key Details
Gender
All
Age Range
19 Years - Any
Study Type
OBSERVATIONAL
Enrollment
267
Start Date
2022-01-01
Completion Date
2026-08-28
Last Updated
2025-08-06
Healthy Volunteers
No
Conditions
Interventions
CPAP (all patients receive CPAP as part of routine clinical care)
Continuous positive airway pressure
Locations (1)
Yale New Haven Hospital Sleep Center
North Haven, Connecticut, United States