Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT05067088

Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness

Sponsor: Yale University

View on ClinicalTrials.gov

Summary

Millions of Americans suffer from high blood pressure, diabetes, strokes and motor vehicle accidents due to ineffective treatment of obstructive sleep apnea (OSA). Our preliminary data suggest that physiological causes of OSA such as easy arousability (low arousal threshold) or unstable breathing control (high loop gain) may influence effectiveness of OSA's most common treatment, continuous positive airway pressure (CPAP). The NICE-PAP study will examine how the physiologic traits that cause OSA in each individual impact CPAP effectiveness and can lead to personalized OSA treatments that improve patient lives.

Official title: Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness: NICEPAP Study Prospective Cohort

Key Details

Gender

All

Age Range

19 Years - Any

Study Type

OBSERVATIONAL

Enrollment

267

Start Date

2022-01-01

Completion Date

2026-08-28

Last Updated

2025-08-06

Healthy Volunteers

No

Interventions

OTHER

CPAP (all patients receive CPAP as part of routine clinical care)

Continuous positive airway pressure

Locations (1)

Yale New Haven Hospital Sleep Center

North Haven, Connecticut, United States