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18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor
Sponsor: Peking Union Medical College Hospital
Summary
The aim of this study is to evaluate the diagnostic performance and tumor burden of 18F-metafluorobenzylguanidine (18F-MFBG) positron emission tomography (PET) in patients with neuroendocrine tumors mainly in pheochromocytoma and paraganglioma (PPGL) and neuroblastoma (NB).
Official title: A Study of 18F-MFBG Imaging for the Tumor Burden Evaluation or Diagnostic Performance in Pheochromocytoma, Paraganglioma and Neuroblastoma.
Key Details
Gender
All
Age Range
1 Year - 80 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2021-09-01
Completion Date
2026-12
Last Updated
2024-03-01
Healthy Volunteers
No
Interventions
18F-MFBG
Patients with neuroendocrine malignancies receive 2-4 MBq/kg of 18F-MFBG intravenously followed by PET/CT after 60min of injection.
68Ga-Dotatate
Patients with malignant PPGL and NB receive intravenously 68Ga-Dotatate followed by PET/CT after 40min of injection.
Locations (1)
Peking union medical college hospital
Beijing, Dongcheng, China