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RECRUITING
NCT05069220
EARLY_PHASE1

18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor

Sponsor: Peking Union Medical College Hospital

View on ClinicalTrials.gov

Summary

The aim of this study is to evaluate the diagnostic performance and tumor burden of 18F-metafluorobenzylguanidine (18F-MFBG) positron emission tomography (PET) in patients with neuroendocrine tumors mainly in pheochromocytoma and paraganglioma (PPGL) and neuroblastoma (NB).

Official title: A Study of 18F-MFBG Imaging for the Tumor Burden Evaluation or Diagnostic Performance in Pheochromocytoma, Paraganglioma and Neuroblastoma.

Key Details

Gender

All

Age Range

1 Year - 80 Years

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2021-09-01

Completion Date

2026-12

Last Updated

2024-03-01

Healthy Volunteers

No

Interventions

DRUG

18F-MFBG

Patients with neuroendocrine malignancies receive 2-4 MBq/kg of 18F-MFBG intravenously followed by PET/CT after 60min of injection.

DRUG

68Ga-Dotatate

Patients with malignant PPGL and NB receive intravenously 68Ga-Dotatate followed by PET/CT after 40min of injection.

Locations (1)

Peking union medical college hospital

Beijing, Dongcheng, China