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RECRUITING
NCT05072262
PHASE4

DSAEK/DMEK and Cystoid Macular Edema - the Role for Topical NSAIDs (Nepafenac) (DMEC)

Sponsor: Oslo University Hospital

View on ClinicalTrials.gov

Summary

The DMEC trial is a randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in patients undergoing corneal endothelial transplantations (DSAEK or DMEK).

Official title: A Randomized Clinical Two-arm Trial Comparing Inflammation and Cystoid Macular Edema for the Medication Regimens Postoperative Topical NSAIDs and Steroids to Only Postoperative Topical Steroids in Patients Undergoing Corneal Endothelial Transplantations (DMEC)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2022-11-25

Completion Date

2026-10

Last Updated

2022-12-01

Healthy Volunteers

No

Interventions

DRUG

Nepafenac Ophthalmic

Topical nepafenac (Nevanac) 3 mg/ml

DRUG

Dexamethasone Ophthalmic

Topical dexamethasone 1 mg/ml (Spersadex)

Locations (1)

Department of Ophthalmology, Oslo University Hospital

Oslo, Norway