Clinical Research Directory

Inclusion Criteria: * Adult primary liver transplant recipients of DBD or DCD donor Livers perfused on OCS Liver System Donor Exclusion Criteria: * Donor livers with accessory arterial blood supply requiring back table anastomosis, major traumatic injury, or hematoma; or * Split donor liver; or * DCD donor liver with \>30 minutes of warm ischemic time (defined as from withdrawal of life support until donor liver cold flush); or * DCD donors age \>55 years; or * DCD donor liver with macrosteatosis of \>15% * Living donors * Donors with positive serology for HIV, Hep B and C * Donors with macrosteatosis of ≥40% Recipient Exclusion Criteria: * Fulminant liver failure; or * Concurrent (multi-organ transplant) or previous solid organ or bone marrow transplant; or * Chronic renal dialysis at time of transplant; or * Dependency on more than 1 inotropic agent to maintain hemodynamics; or * Ventilator dependent at time of transplant.