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Exercise as a Primer for Brain Stimulation in Vascular Cognitive Impairment No Dementia (VCIND)
Sponsor: Sunnybrook Health Sciences Centre
Summary
People with vascular conditions are at risk of having memory problems, and these memory problems increase the risk for further cognitive decline. Brain stimulation has been used to improve mood and memory. Transcranial direct current stimulation (tDCS) is believed to work best on brain cells that are active or "primed" before stimulation. The purpose of this study is to compare the effects of exercise and tDCS on memory performance in patients who have completed cardiac rehabilitation and are at risk of cognitive decline.
Official title: Exercise as a Primer for Excitatory Stimulation Study in Vascular Cognitive Impairment No Dementia (EXPRESS-V)
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2021-11-22
Completion Date
2026-12
Last Updated
2025-05-22
Healthy Volunteers
No
Interventions
tDCS
All participants randomized to tDCS will receive active tDCS
Exercise
Participants will exercise at Toronto Rehab.
Sham stimulation
The same procedure for tDCS will be used for the sham condition, except without active current.
Treatment as usual
Exercise education/ treatment as usual will include routine advice about physical activity.
Locations (1)
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada