Clinical Research Directory

Inclusion Criteria: * Age \> 18 * Patients with performed allogeneic stem cell transplantation any type of donor, stem cell source, GVHD prophylaxis or conditioning regimen and at least at day +20 after HCT. * Hematologic Remission after HCT at study entrance, MRD positive patients are allowed to enter the study * Eastern Cooperative Oncology Group (ECOG) performance status of 0-3 * Signature of informed and written consent by the subject or by the subject's legally acceptable representative for patients under guardianship or trusteeship to participate in the study * Access to an internet connected device (smartphone/tablet/computer) * Able to understand and communicate in the respective language * Consent to use a wearable device through the time of the study * Consent to use a chatbot application for both healthcare data exchange and psychologic intervention Exclusion Criteria: * Missing consent to use a wearable device and contribute personal data collected at the point of life to the study * ECOG performance status of 4 * Relapse of the disease at study inclusion * Uncontrolled systemic infection * Diagnosis of a secondary malignancy requiring systemic therapy * Reported ongoing severe depression or potential suicidal ideation * Vulnerable patients such as: minor, persons deprived of liberty, persons in Intensive Care Unit unable to provided informed consent prior to the intervention * Other ongoing interventional protocol that might interfere with the current study primary endpoint