Clinical Research Directory

Inclusion Criteria: 1. Age 18 to 75, men and women; 2. Patients with clinical symptoms of degree I-Ⅲ internal hemorrhoids confirmed after medical history collection, clinical examination or colonoscopy; 3. The patient was willing to receive minimally invasive treatment for internal hemorrhoids and sign informed consent by himself or his legal agent. Exclusion Criteria: 1. Age \<18 or age\> 75; 2. External hemorrhoids or mixed hemorrhoids; 3. degree Ⅳ internal hemorrhoids 4. Unsymptomatic internal hemorrhoids 5. Internal hemorrhoids were combined with complications such as chimerism, thrombosis, ulceration, or infection； 6. Poor basic conditions can not tolerate endoscopic treatment, such as serious cardiovascular and cerebrovascular diseases, respiratory dysfunction, liver and kidney failure, mental disorders, etc.; 7. There are other serious diseases involving the rectum and anus, such as anal fistula, perianal infection, anal stenosis, inflammatory bowel disease activity period, colorectal tumors, etc.; 8. Patients with severe coagulation dysfunction or long-term oral anticoagulant drugs or antiplatelet aggregation drugs without withdrawal; 9. Women in pregnancy or puerperium; 10. Hardening agent allergy patients, such as polycininol, etc; 11. Previous history of endoscopic treatment of hemorrhoid disease, surgical history or other low rectal and anal surgery history; 12. The patient was unwilling to receive endoscopic treatment for internal hemorrhoids, and himself or his legal agent refused to sign the informed consent form.