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RECRUITING
NCT05090345

A Prospective Registry of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (MODS).

Sponsor: Duke University

View on ClinicalTrials.gov

Summary

This is a prospective international multi-center registry and biorepository trial of children and adolescents/young adults (AYA) undergoing hematopoietic cell transplantation (HCT) to assess the impact of endotheliopathies in the HCT setting as a contributor of significant morbidity and mortality.

Official title: Prospective Multi Center Study of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (MODS)

Key Details

Gender

All

Age Range

0 Years - 26 Years

Study Type

OBSERVATIONAL

Enrollment

500

Start Date

2019-11-19

Completion Date

2026-02-05

Last Updated

2025-04-20

Healthy Volunteers

No

Interventions

OTHER

Biorepository Trial

participating in this arm, peripheral blood specimen(s) will be obtained at 8 specified time-points.

Locations (3)

Mayo Clinic

Rochester, Minnesota, United States

Duke University

Durham, North Carolina, United States

MD Anderson Cancer Center

Houston, Texas, United States