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A Prospective Registry of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (MODS).
Sponsor: Duke University
Summary
This is a prospective international multi-center registry and biorepository trial of children and adolescents/young adults (AYA) undergoing hematopoietic cell transplantation (HCT) to assess the impact of endotheliopathies in the HCT setting as a contributor of significant morbidity and mortality.
Official title: Prospective Multi Center Study of Pediatric Cellular Therapy Patients at Risk for Endothelial Dysfunction, Sinusoidal Obstruction Syndrome and/or Multi-Organ Dysfunction Syndrome (MODS)
Key Details
Gender
All
Age Range
0 Years - 26 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2019-11-19
Completion Date
2026-02-05
Last Updated
2025-04-20
Healthy Volunteers
No
Conditions
Interventions
Biorepository Trial
participating in this arm, peripheral blood specimen(s) will be obtained at 8 specified time-points.
Locations (3)
Mayo Clinic
Rochester, Minnesota, United States
Duke University
Durham, North Carolina, United States
MD Anderson Cancer Center
Houston, Texas, United States