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ENROLLING BY INVITATION
NCT05092100
NA

Neural Mechanisms for Reducing Interference During Episodic Memory Formation

Sponsor: University of Oregon

View on ClinicalTrials.gov

Summary

Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory. Recruitment will involve emails, flyers, and local advertisements. Individuals between the ages of 18-80 (or 18-35 for some studies) will be eligible. The broad objective of the research is to understand how humans form distinct memories for similar experiences. Experimental sessions will involve studying and trying to remember various images (e.g., images of natural scenes). The intervention will involve manipulating the similarity and/or learning protocol for the studied images. Outcome measures will include (a) behavioral measures of memory, and/or (b) fMRI measures of hemodynamic activity, and/or (c) eye tracking measures of gaze direction. Experimental sessions will last approximately 1-3 hours.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

737

Start Date

2021-09-29

Completion Date

2026-01

Last Updated

2024-09-19

Healthy Volunteers

Yes

Conditions

Interventions

BEHAVIORAL

Visual stimulus similarity

Visual stimulus similarity will be varied in order to test for effects on memory. Learning protocol (the order and frequency with which stimuli are learned) will also be varied.

OTHER

fMRI

fMRI will be used to measure patterns of BOLD activity during learning.

BEHAVIORAL

Eye tracking

Eye tracking will be used to measure patterns of eye movements when viewing images.

Locations (1)

University of Oregon

Eugene, Oregon, United States