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Neural Mechanisms for Reducing Interference During Episodic Memory Formation
Sponsor: University of Oregon
Summary
Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory. Recruitment will involve emails, flyers, and local advertisements. Individuals between the ages of 18-80 (or 18-35 for some studies) will be eligible. The broad objective of the research is to understand how humans form distinct memories for similar experiences. Experimental sessions will involve studying and trying to remember various images (e.g., images of natural scenes). The intervention will involve manipulating the similarity and/or learning protocol for the studied images. Outcome measures will include (a) behavioral measures of memory, and/or (b) fMRI measures of hemodynamic activity, and/or (c) eye tracking measures of gaze direction. Experimental sessions will last approximately 1-3 hours.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
737
Start Date
2021-09-29
Completion Date
2026-01
Last Updated
2024-09-19
Healthy Volunteers
Yes
Conditions
Interventions
Visual stimulus similarity
Visual stimulus similarity will be varied in order to test for effects on memory. Learning protocol (the order and frequency with which stimuli are learned) will also be varied.
fMRI
fMRI will be used to measure patterns of BOLD activity during learning.
Eye tracking
Eye tracking will be used to measure patterns of eye movements when viewing images.
Locations (1)
University of Oregon
Eugene, Oregon, United States