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Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT
Sponsor: Medical University of South Carolina
Summary
This is a clinical trial for chronic pancreatitis (CP) patients undergoing total pancreatectomy with islet autotransplantation (TP-IAT). Participants will be randomized to either bone marrow-derived mesenchymal stem cells (MSCs) or control with the standard of care. Participants will be followed for one-year post-transplant.
Official title: Autologous Mesenchymal Stromal Cells and Islet Co-transplantation to Enhance Islet Survival and Function in Chronic Pancreatitis Patients Undergo Total Pancreatectomy and Islet Autotransplantation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2021-12-01
Completion Date
2027-06-30
Last Updated
2026-02-05
Healthy Volunteers
No
Interventions
Bone marrow-derived mesenchymal stem cells
MSC transplantation
Placebo
Standard of Care
Locations (1)
Medical University of South Carolina
Charleston, South Carolina, United States