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RECRUITING
NCT05096351

Immunological Reaction of the Recipient After Cold-stored Saphenous Venous Allograft (Bioprotec)

Sponsor: Centre Hospitalier Universitaire de Nīmes

View on ClinicalTrials.gov

Summary

The study investigators propose to perform a blood test before and after allograft placement in all patients receiving a cold-stored venous allografts at the University Hospital of Nîmes to study the occurrence of FVFA-related ASD in these patients. The aim of this work is to characterize a possible immune reaction generated by the implantation of venous allografts prepared according to the BIOPROTEC method. In case of a proven immune reaction, the study will allow a modification of our current attitude and to exclude patients potentially eligible for renal transplantation at the time of venous allograft placement, or to perform in these patients an allo-compatibility test with the venous allograft preoperatively and thus protect these patients from an increased risk of subsequent organ transplant rejection.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2022-06-08

Completion Date

2025-12

Last Updated

2024-05-06

Healthy Volunteers

No

Interventions

OTHER

Blood test

Collection of blood samples at 1 and 6 months for HLA typing for donor and recipient antibodies

Locations (1)

CHU de Nîmes

Nîmes, France