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Immunological Reaction of the Recipient After Cold-stored Saphenous Venous Allograft (Bioprotec)
Sponsor: Centre Hospitalier Universitaire de Nīmes
Summary
The study investigators propose to perform a blood test before and after allograft placement in all patients receiving a cold-stored venous allografts at the University Hospital of Nîmes to study the occurrence of FVFA-related ASD in these patients. The aim of this work is to characterize a possible immune reaction generated by the implantation of venous allografts prepared according to the BIOPROTEC method. In case of a proven immune reaction, the study will allow a modification of our current attitude and to exclude patients potentially eligible for renal transplantation at the time of venous allograft placement, or to perform in these patients an allo-compatibility test with the venous allograft preoperatively and thus protect these patients from an increased risk of subsequent organ transplant rejection.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2022-06-08
Completion Date
2025-12
Last Updated
2024-05-06
Healthy Volunteers
No
Conditions
Interventions
Blood test
Collection of blood samples at 1 and 6 months for HLA typing for donor and recipient antibodies
Locations (1)
CHU de Nîmes
Nîmes, France