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COMPLETED
NCT05098041
PHASE1

A Study of Soticlestat and Rifampin in Healthy Adults

Sponsor: Takeda

View on ClinicalTrials.gov

Summary

The main aim of this study is to check how rifampin affects the way soticlestat is processed by the body. Participants will be required to stay at the study clinic for 18 consecutive days. On the first full day and 15th day, participants will take a single dose of soticlestat. Rifampin will be taken each day starting on the 5th day for 13 consecutive days. Clinic staff will follow up with each participant about 15 days after the last soticlestat dose to check for any side effects.

Official title: A Phase 1 Open-Label Study to Evaluate the Drug-Drug Interaction of Rifampin as a Strong CYP3A Inducer on Soticlestat Pharmacokinetics in Healthy Adult Participants

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

15

Start Date

2021-11-22

Completion Date

2022-03-03

Last Updated

2026-09-10

Healthy Volunteers

Yes

Interventions

DRUG

Soticlestat

Soticlestat tablets.

DRUG

Rifampin

Rifampin capsules.

Locations (1)

Celerion

Belfast, United Kingdom