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The Human Sperm Survival Assay (HSSA) as an Internal Quality Control for the IVF Consumables (REPROTOX 2)
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche
Summary
The main embryotoxicity quality controls are the mouse embryo test (MEA = Mouse Embryo Assay) and the human sperm survival test (HSSA = Human Sperm Survival Assay). The HSSA test measures the survival (or mobility) of human sperm after exposure to the tested consumable for a predetermined period of time and compares it to that of unexposed sperm. It would appear that the HSSA is comparable in terms of sensitivity to the MEA test for the detection of toxicity.
Official title: The Human Sperm Survival Assay (HSSA) as an Internal Quality Control for the IVF Consumables
Key Details
Gender
MALE
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
826
Start Date
2021-03-10
Completion Date
2023-01-16
Last Updated
2026-07-16
Healthy Volunteers
Not specified
Interventions
HSSA test
Human Sperm Survival Assay testing performed on different batches of different types of IVF consumables. In practice, 3 consumables from the same batch will be tested with 3 different sperms to ensure the repeatability of the result / test.
Locations (1)
Private Hospital of Parly II-Le Chesnay
Le Chesnay, France