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RECRUITING
NCT05108818
PHASE4

Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults

Sponsor: University of Pennsylvania

View on ClinicalTrials.gov

Summary

Cellular and humoral immune responses before and after seasonal influenza vaccination will be assessed. Each year, up to 100 participants will be enrolled. To study age-specific differences in immune responses, participants with various years of birth will be enrolled. The investigators hypothesize that humans with different birth years will mount antibody and cellular responses of different specificities following seasonal influenza vaccination.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

700

Start Date

2021-10-07

Completion Date

2028-03-31

Last Updated

2026-02-09

Healthy Volunteers

Yes

Interventions

BIOLOGICAL

Seasonal influenza vaccine

The seasonal influenza vaccine is administered intramuscularly at a dose of 15 ug of HA per component, as approved by the FDA.

Locations (1)

University of Pennsylvania

Philadelphia, Pennsylvania, United States