Clinical Research Directory
Browse clinical research sites, groups, and studies.
Monitoring of Progesterone Administered in Infertile Patients During a Cycle of Frozen Embryo Transfer.
Sponsor: University Hospital, Toulouse
Summary
During an In Vitro Fertilization (IVF) attempt, several embryos are obtained but not all of them can be transferred to the uterus in the same cycle due to the risk of multiple pregnancies. Thus, it is very common for these couples to benefit from cryopreservation. Patients scheduled for frozen embryo transfer (TEC) receive estrogen and progesterone replacement therapy to prepare the endometrium for implantation. Data from the literature recently showed that low progesterone on the day of embryo transfer was responsible for a significantly higher rate of implantation failure and miscarriage.
Official title: Monitoring of Progesterone Administered in Infertile Patients During a Cycle of Frozen Embryo Transfer: a Population Pharmacokinetic Study.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2021-12-07
Completion Date
2022-06-03
Last Updated
2026-05-07
Healthy Volunteers
No
Conditions
Interventions
Questionnaire
A questionnaire will be offered to patients and identify the schedules of administration of progesterone, the day and time of blood samples taken as part of the care, the potential adverse events associated with this administration.
Locations (1)
CHU Toulouse
Toulouse, France