Clinical Research Directory

Inclusion Criteria: All patients: * Adults (\>18 years) * Presenting with cutaneous psoriasis * Patients have signed an informed consent * Beneficiary of the health insurance, except for the AME Only for patients of Group 1 * Patients require systemic treatment for psoriasis * Patients are naïve to biological therapies Only for patients of Group 2: * Patients requiring treatment with anti-IL-23 biologics (guselkumab, risankizumab, tildrakizumab) upon referent physician's decision. * Patients are naïve to biological therapies or have received only one biologic, with a "wash-out" period of at least 4 months Non inclusion Criteria: For all : * Patient is minor * Patient is pregnant or breastfeeding * Patient is immunocompromised * Patient is under legal protection, curatorship, guardianship * Patient refuses consent * Patient is unable to comply with study requirements for geographic, social or psychiatric reason. * Beneficiary of the AME Only for patients of Group 1 * Patient has received biologics Only for patients of Group 2 * Patient has a contraindication to the chosen biotherapy * Patient has received biologics within the last 4 months * Patient has been treated with 2 or more biologics * Patient has already received an anti-IL-23 biologic