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NOT YET RECRUITING
NCT05114785

Heart Failure With Preserved Ejection Fraction: Evaluation and Recognition by CMR

Sponsor: University of East Anglia

View on ClinicalTrials.gov

Summary

Heart failure with preserved ejection fraction (HFpEF) is a common and growing condition with a poor prognosis but the pathophysiology and management are still being investigated. The PREFER-CMR project aims to evaluate and validate the application of novel 4D cardiac magnetic resonance flow dynamic methods to measure left ventricular pressures and validate these measurements with direct pressure measurement by coronary angiography. This is a prospective observational study of patients with HFpEF undergoing clinical evaluation with coronary angiography who will also undergo contemporaneous cardiac MRI. The primary outcome will be the level of agreement between the two methods using angiography as the reference method.

Official title: PReserved Ejection Fraction Evaluation and Recognition by Cardiac Magnetic Resonance

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2022-01

Completion Date

2032-01

Last Updated

2022-01-05

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Multi Parametric Cardiac Magnetic Resonance

Research based Cardiac MRI evaluation to determine cardiovascular haemodynamics