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Heart Failure With Preserved Ejection Fraction: Evaluation and Recognition by CMR
Sponsor: University of East Anglia
Summary
Heart failure with preserved ejection fraction (HFpEF) is a common and growing condition with a poor prognosis but the pathophysiology and management are still being investigated. The PREFER-CMR project aims to evaluate and validate the application of novel 4D cardiac magnetic resonance flow dynamic methods to measure left ventricular pressures and validate these measurements with direct pressure measurement by coronary angiography. This is a prospective observational study of patients with HFpEF undergoing clinical evaluation with coronary angiography who will also undergo contemporaneous cardiac MRI. The primary outcome will be the level of agreement between the two methods using angiography as the reference method.
Official title: PReserved Ejection Fraction Evaluation and Recognition by Cardiac Magnetic Resonance
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2022-01
Completion Date
2032-01
Last Updated
2022-01-05
Healthy Volunteers
No
Interventions
Multi Parametric Cardiac Magnetic Resonance
Research based Cardiac MRI evaluation to determine cardiovascular haemodynamics