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Pre-emptive Intravenous Morphine for Acute Post-craniotomy Pain.
Sponsor: Tel-Aviv Sourasky Medical Center
Summary
We propose a double-blind randomized controlled trial to evaluate the effect of intravenously administered morphine at surgery conclusion on acute postoperative pain in patients recovering from craniotomy surgery. Participating adults having craniotomy surgery will be randomized in a 1:1 ratio to intraoperative intravenous administration of 0.08 mg/kg morphine at dura closure, or a matching placebo.
Official title: Pre-emptive Intravenous Morphine for Acute Post-craniotomy Pain: a Randomized, Double-blind, Placebo-controlled Trial.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
115
Start Date
2022-02-16
Completion Date
2025-05-01
Last Updated
2024-11-20
Healthy Volunteers
No
Conditions
Interventions
Morphine
Intraoperative intravenous administration of 0.08 mg/kg morphine at dura closure.
Nacl 0.9%
Intraoperative intravenous administration of 0.08 ml/kg NaCl 0.9% at dura closure.
Locations (1)
Tel-Aviv Medical Center, Sackler faculty of medicine, Tel-Aviv University, Israel
Tel Aviv, Israel