Clinical Research Directory

Inclusion Criteria: 1. Age 40 or greater 2. Clinical diagnosis of COPD 3. Hospitalized for acute exacerbation of COPD. 4. Be willing to adhere to trial and follow-up procedures and give informed consent Exclusion Criteria: 1. Secondary diagnosis of congestive heart failure that is severe as documented by active symptoms, New York Heart Association (NYHA) functional classification IV or left ventricular ejection fraction \<25% on echocardiography 2. Other respiratory conditions that could confound the diagnosis such as asthma, pulmonary fibrosis, bronchiectasis, and lung cancer. Participants with pneumonic exacerbations of COPD will be included. 3. Primary diagnosis of COVID pneumonia. Individuals with incidentally detected COVID or persistently positive for COVID but deemed to be convalescent will not be excluded. 4. Active cancers on chemotherapy or radiation therapy 5. Immunosuppressed states predisposing to frequent hospitalizations including uncontrolled HIV/AIDS 6. Active or recent (within 1 month) myocardial infarction 7. Angina not well-controlled by medication 8. Unstable cardiac arrhythmias, atrial or ventricular 9. Supplemental oxygen requirement greater than 5 liters per minute at either rest or with exertion 10. Significant cognitive dysfunction, including dementia, that in opinion of investigator would impair ability to safely or effectively engage in study protocol 11. Participants with any terminal medical illnesses as diagnosed by a physician, and/or on hospice 12. Currently enrolled in and participating in pulmonary rehabilitation 13. Treatment with chronic or newly initiated home ventilatory support. Those on in-patient short-term non-invasive ventilation will not be excluded. 14. Special patient groups such as prisoners and institutionalized patients 15. Participants with musculoskeletal comorbidities or physical infirmities that preclude participation in an exercise program 16. Current participation in any other interventional clinical trial 17. Inability to understand and speak English during exercise sessions 18. Inability or unwillingness to comply with study and/or follow-up procedures outlined in the protocol