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Continuous Erector Spinae Plane Blocks to Treat Pain Following Percutaneous Nephrolithotomy
Sponsor: University of California, San Diego
Summary
This is a randomized, triple-masked, placebo-controlled parallel-arm human subjects clinical trial investigating the addition of a continuous erector spinae plane nerve block to a single-injection erector spinae plane block to provide postoperative analgesia following percutaneous nephrolithotomy. Participants will all receive a single-injection nerve block and perineural catheter insertion. Following surgery, participants will be randomly allocated to receive either perineural local anesthetic or normal saline until the second day following surgery.
Official title: Continuous Erector Spinae Plane Blocks to Treat Pain Following Percutaneous Nephrolithotomy: A Randomized, Placebo-controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2022-03-16
Completion Date
2025-11-08
Last Updated
2026-10-07
Healthy Volunteers
No
Conditions
Interventions
Active bupivacaine 0.25% via an erector spinae plane perineural catheter
Administration of bupivacaine 0.25% through a perineural catheter inserted into the erector spinae plane (programmed intermittent bolus of 21 mL every 4 hours and no patient-controlled bolus)
Placebo normal saline via an erector spinae plane perineural catheter
Administration of normal saline through a perineural catheter inserted into the erector spinae plane (programmed intermittent bolus of 21 mL every 4 hours and no patient-controlled bolus)
Locations (2)
UC San Diego
San Diego, California, United States
University of California, San Diego
San Diego, California, United States