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Resilience and Brain Health of Older Adults (MEDEX-2)
Sponsor: Washington University School of Medicine
Summary
This project capitalizes on a natural experiment imposed by the COVID-19 pandemic in conjunction with an extensive set of cognitive, emotional, biological, and neuroimaging variables already collected at multiple time points in older adults participating in a clinical trial of exercise and mindfulness. This project will elucidate the effects of stress on cognitive function and emotional health in later life, including biological measures of Alzheimer Disease risk, stress, and aging, with the ultimate goal of discovering how to mitigate these effects, among older adults who have made and maintained a lifestyle change.
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
468
Start Date
2019-04-16
Completion Date
2026-08-31
Last Updated
2025-06-18
Healthy Volunteers
No
Conditions
Interventions
Mindfulness-Based Stress Reduction
Mindfulness-Based Stress Reduction
Exercise
Exercise
Mindfulness-Based Stress Reduction + Exercise
Mindfulness-Based Stress Reduction + Exercise
Health Education
Health Education
Locations (1)
Washington University School of Medicine
St Louis, Missouri, United States