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ACTIVE NOT RECRUITING
NCT05125510

The Canadian COVID-19 Prospective Cohort Study

Sponsor: University Health Network, Toronto

View on ClinicalTrials.gov

Summary

The CANCOV study will be the first Canadian study to provide a comprehensive evaluation of early, and 1-year, outcomes of outpatient and hospitalized COVID-19 survivors and their family caregivers, their varied trajectories and associated clinical risk factors. The overall objectives are to determine short- (in hospital) and longer-term (1, 3, 6 and 12 months post-acute hospital discharge) outcomes COVID-19+ patients across the spectrum of symptom severity, including outpatients and inpatients from GIM and ICU wards and their caregivers, and the clinical, sociodemographic, multi-omic predictors of these outcomes. By leveraging expertise from investigators across disciplines and divisions, this study presents a suite of complementary projects that explore the genetic, transcriptomic, epigenomic and immunologic evaluation of COVID-19 infection across the illness and recovery trajectory during the acute illness and in the context of multidimensional long-term outcomes. As there continues to be need for longer term follow up and research on Long-COVID, this study has added an optional extension to include 2-year, 3-year, 4-year and 5 year outcomes.

Key Details

Gender

All

Age Range

16 Years - Any

Study Type

OBSERVATIONAL

Enrollment

2176

Start Date

2020-06-17

Completion Date

2027-12

Last Updated

2025-08-14

Healthy Volunteers

No

Conditions

Locations (14)

Alberta Health Services

Calgary, Alberta, Canada

Providence Healthcare

Vancouver, British Columbia, Canada

Health Sciences Centre and St. Boniface Hospital and Grace Hospital

Winnipeg, Manitoba, Canada

William Osler Health System

Etobicoke, Ontario, Canada

St Joseph's Health Centre

Hamilton, Ontario, Canada

The Ottawa Hospital

Ottawa, Ontario, Canada

Unity Health (St Michaels Health Centre_

Toronto, Ontario, Canada

Mount Sinai Hospital

Toronto, Ontario, Canada

University Health Network, Osteoporosis Department

Toronto, Ontario, Canada

Hospital for Sick Children

Toronto, Ontario, Canada

Michael Garron Hospital

Toronto, Ontario, Canada

McGill University Health Centre

Montreal, Quebec, Canada

Montreal Jewish General

Montreal, Quebec, Canada

University of Sherbrooke

Sherbrooke, Quebec, Canada