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ENROLLING BY INVITATION
NCT05132660
EARLY_PHASE1
Treating Early Stage Diabetic Retinopathy
Sponsor: VA Office of Research and Development
View on ClinicalTrials.gov
Summary
To determine if levodopa will slow the appearance of blood vessel changes in the eyes of patients with diabetes. Treatment will be started in patients with diabetes show delays in the electrical activity of the retina when measured non-invasively with a electroretinogram.
Key Details
Gender
All
Age Range
30 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
244
Start Date
2022-07-01
Completion Date
2028-12-31
Last Updated
2026-04-07
Healthy Volunteers
No
Conditions
Interventions
DRUG
Sinemet CR
25 mg carbidopa/100 mg levodopa
DRUG
placebo
Placebo pill of similar size/shape
Locations (1)
Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgia, United States