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AN/BN Risk Factors Study
Sponsor: Stanford University
Summary
Across the United States, thousands of children and adolescents suffer from eating disorders. Among young women alone, an estimated 2 to 4 percent are dealing with anorexia nervosa. Anorexia nervosa also has the highest mortality rate of any psychiatric disorder and produces a six-fold increased risk for death. Unfortunately, study shows that current treatments are only successful with 25 percent of patients and no eating disorder prevention program has been found to reduce future onset of anorexia nervosa. The goal of this study is to conduct a highly innovative pilot study that will identify risk factors that predict future onset of anorexia nervosa and investigate how the risk processes for anorexia nervosa are different from the risk processes for bulimia nervosa. The proposed pilot study will: * Compare 30 healthy adolescent girls at high risk for anorexia nervosa to 30 healthy adolescent girls at high risk for bulimia nervosa, and 30 healthy adolescent girls at low risk for eating disorder in an effort to document risk processes that are present in early adolescence before anorexia nervosa typically emerges. * Test whether elevations in the hypothesized risk factors predict future onset of anorexia nervosa over a four-year follow-up.
Official title: Identifying Risk Factors That Predict Onset of Anorexia Nervosa and Bulimia Nervosa
Key Details
Gender
FEMALE
Age Range
12 Years - 16 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2021-11-23
Completion Date
2029-05-26
Last Updated
2025-08-28
Healthy Volunteers
Yes
Conditions
Interventions
GE MR Scanner
3T GE MR 750 systems MR scanner Scanners run compatible software so pulse sequences and reconstructions can easily be supported on all systems. Reconstruction servers are networked to all scanners for reconstruction and data archiving. 3T scanner is equipped with state-of-the-art gradient systems (at least 40 mT/m Gradients / 150 mT/m/ms slew rates) and 16 or more receive channels. 3T scanner includes an assortment of RF coils including quadrature and phased-array coils designed to image brain, spine, neurovascular, torso, pelvis, cardiac, knee, foot/ankle, and hand/wrist. 3T system has several sizes of 16-channel "wrap" coils that are excellent for scans using parallel imaging.
Locations (1)
Stanford University
Stanford, California, United States