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ACTIVE NOT RECRUITING
NCT05133037

AN/BN Risk Factors Study

Sponsor: Stanford University

View on ClinicalTrials.gov

Summary

Across the United States, thousands of children and adolescents suffer from eating disorders. Among young women alone, an estimated 2 to 4 percent are dealing with anorexia nervosa. Anorexia nervosa also has the highest mortality rate of any psychiatric disorder and produces a six-fold increased risk for death. Unfortunately, study shows that current treatments are only successful with 25 percent of patients and no eating disorder prevention program has been found to reduce future onset of anorexia nervosa. The goal of this study is to conduct a highly innovative pilot study that will identify risk factors that predict future onset of anorexia nervosa and investigate how the risk processes for anorexia nervosa are different from the risk processes for bulimia nervosa. The proposed pilot study will: * Compare 30 healthy adolescent girls at high risk for anorexia nervosa to 30 healthy adolescent girls at high risk for bulimia nervosa, and 30 healthy adolescent girls at low risk for eating disorder in an effort to document risk processes that are present in early adolescence before anorexia nervosa typically emerges. * Test whether elevations in the hypothesized risk factors predict future onset of anorexia nervosa over a four-year follow-up.

Official title: Identifying Risk Factors That Predict Onset of Anorexia Nervosa and Bulimia Nervosa

Key Details

Gender

FEMALE

Age Range

12 Years - 16 Years

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2021-11-23

Completion Date

2029-05-26

Last Updated

2025-08-28

Healthy Volunteers

Yes

Interventions

DEVICE

GE MR Scanner

3T GE MR 750 systems MR scanner Scanners run compatible software so pulse sequences and reconstructions can easily be supported on all systems. Reconstruction servers are networked to all scanners for reconstruction and data archiving. 3T scanner is equipped with state-of-the-art gradient systems (at least 40 mT/m Gradients / 150 mT/m/ms slew rates) and 16 or more receive channels. 3T scanner includes an assortment of RF coils including quadrature and phased-array coils designed to image brain, spine, neurovascular, torso, pelvis, cardiac, knee, foot/ankle, and hand/wrist. 3T system has several sizes of 16-channel "wrap" coils that are excellent for scans using parallel imaging.

Locations (1)

Stanford University

Stanford, California, United States