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ACTIVE NOT RECRUITING
NCT05138991
NA

Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors

Sponsor: City of Hope Medical Center

View on ClinicalTrials.gov

Summary

The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in the clinic to currently available screening tests for heart failure including echocardiogram (echo) and cardiovascular magnetic resonance (CMR). The SphygmoCor® Xcel and Oscar 2™ systems may help detect cardiac dysfunction earlier than other available screening tests because it can be self-administered outside of the clinic. This study aims to test the accuracy and practicality of these devices in the clinic setting and at home.

Official title: Assessment of the Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

149

Start Date

2022-06-22

Completion Date

2026-07-16

Last Updated

2025-09-23

Healthy Volunteers

Yes

Interventions

PROCEDURE

Echocardiogram Recording

Undergo assessment via echo

OTHER

Questionnaire Administration

Ancillary Studies

PROCEDURE

Stress Cardiac Magnetic Resonance Imaging

Undergo assessment via CMR

DEVICE

Wireless Synchronized Cardiac Function Monitoring Device

SphygmoCor® Xcel Oscar 2™ Ambulatory Blood Pressure Monitor

Locations (1)

City of Hope Medical Center

Duarte, California, United States