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Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors
Sponsor: City of Hope Medical Center
Summary
The clinical trial compares the reproducibility and accuracy of cardiac tonometry-based portable systems that may detect early cardiac dysfunction (SphygmoCor® Xcel and Oscar 2™ ambulatory blood pressure monitor) at home and in the clinic to currently available screening tests for heart failure including echocardiogram (echo) and cardiovascular magnetic resonance (CMR). The SphygmoCor® Xcel and Oscar 2™ systems may help detect cardiac dysfunction earlier than other available screening tests because it can be self-administered outside of the clinic. This study aims to test the accuracy and practicality of these devices in the clinic setting and at home.
Official title: Assessment of the Reproducibility and Accuracy of a Portable System for Early Detection of Cardiac Dysfunction in Childhood Cancer Survivors
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
149
Start Date
2022-06-22
Completion Date
2026-07-16
Last Updated
2025-09-23
Healthy Volunteers
Yes
Interventions
Echocardiogram Recording
Undergo assessment via echo
Questionnaire Administration
Ancillary Studies
Stress Cardiac Magnetic Resonance Imaging
Undergo assessment via CMR
Wireless Synchronized Cardiac Function Monitoring Device
SphygmoCor® Xcel Oscar 2™ Ambulatory Blood Pressure Monitor
Locations (1)
City of Hope Medical Center
Duarte, California, United States