Clinical Research Directory

Inclusion Criteria: 1. Known colorectal adenomas during index colonoscopy; 2. Available baseline M3 and FIT results before index colonoscopy; 3. Aged ≥18 years old; 4. Written informed consent obtained. Exclusion Criteria: 1. Refusal or unfit to undergo surveillance colonoscopy; 2. Incomplete colonoscopy, incomplete removal of colorectal adenomas, or inadequate bowel preparation (defined as Boston Bowel Preparation Scale score 0 or 1 in any colonic segment) at index colonoscopy; 3. Previous colonic resection; 4. Personal history of colorectal cancer; 5. Personal history of polyposis syndrome; 6. Personal history of inflammatory bowel disease; 7. Known pregnancy or lactation; 8. Advanced comorbid conditions (defined as American Society of Anesthesiologists grade 4 or above);