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Investigation of Low-intensity Focused Ultrasound for Human Pain Management
Sponsor: Virginia Polytechnic Institute and State University
Summary
This project examines the effects of noninvasive brain stimulation on pain. The investigators believe this study will help to better understand possible treatments for chronic pain patients. Participants undergo structural imaging, a functional Magnetic Resonance Image (fMRI) and computed tomography (CT). These images are used to align the low-intensity focused ultrasound (LIFU) device which uses sound waves to temporarily change brain activity. Pain testing is done using a small device that will increase/decrease the temperature of the skin. Brain signals are collected using electroencephalography (EEG). Heart rate, blood pressure, and skin moisture will be monitored as well.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2022-02-04
Completion Date
2027-12
Last Updated
2026-03-31
Healthy Volunteers
Yes
Conditions
Interventions
Low Intensity Focused Ultrasound
Application of LIFU
Locations (1)
Fralin Biomedical Research Institute
Roanoke, Virginia, United States