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ENROLLING BY INVITATION
NCT05145426
NA

Investigation of Low-intensity Focused Ultrasound for Human Pain Management

Sponsor: Virginia Polytechnic Institute and State University

View on ClinicalTrials.gov

Summary

This project examines the effects of noninvasive brain stimulation on pain. The investigators believe this study will help to better understand possible treatments for chronic pain patients. Participants undergo structural imaging, a functional Magnetic Resonance Image (fMRI) and computed tomography (CT). These images are used to align the low-intensity focused ultrasound (LIFU) device which uses sound waves to temporarily change brain activity. Pain testing is done using a small device that will increase/decrease the temperature of the skin. Brain signals are collected using electroencephalography (EEG). Heart rate, blood pressure, and skin moisture will be monitored as well.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2022-02-04

Completion Date

2027-12

Last Updated

2026-03-31

Healthy Volunteers

Yes

Conditions

Interventions

DEVICE

Low Intensity Focused Ultrasound

Application of LIFU

Locations (1)

Fralin Biomedical Research Institute

Roanoke, Virginia, United States