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Investigation of the Duration of Low-intensity Focused Ultrasound
Sponsor: Virginia Polytechnic Institute and State University
Summary
This project examines the effects of various durations of noninvasive neuromodulation on muscle contractions. The investigators believe this study will help to better understand noninvasive brain stimulation techniques that may have the potential to aid in addiction, pain, and mental health issues. Participants undergo structural imaging, a functional Magnetic Resonance Image (fMRI) and computed tomography (CT). These images are used to align the low-intensity focused ultrasound (LIFU) and transcranial magnetic stimulation (TMS) devices to temporarily change brain activity. Electromyography (EMG) will be used to record muscle contractions of the hand.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2022-08-26
Completion Date
2026-06
Last Updated
2025-07-04
Healthy Volunteers
Yes
Interventions
Low-Intensity Focused Ultrasound
LIFU application using various durations, responses of neuromodulation recorded using TMS and EMG.
Locations (1)
Fralin Biomedical Research Institute
Roanoke, Virginia, United States