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Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome
Sponsor: CHU de Reims
Summary
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The objective of this study is to test whether awake OSAS patients would exhibit a similar cortical activity. Whether or not such cortical compensatory mechanisms have cognitive consequences would be also analyze.
Official title: Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome, With and Without CPAP, During Wakefulness - Impact on Cognitive Functions
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2023-03-02
Completion Date
2027-07-02
Last Updated
2025-12-02
Healthy Volunteers
Yes
Conditions
Interventions
functional magnetic resonance imaging
functional magnetic resonance imaging
Locations (1)
Chu Reims
Reims, France