Clinical Research Directory

Trajectories and Mechanisms of Recovery From Malaria: An Observational Study

Sponsor: Imperial College London

Summary

This observational research study aims to answer the question: 'Which aspects of human biology play an important role in recovery from symptomatic malaria?' In particular, the researchers aim to identify human genes for which the level of gene activity reflects the patient's overall rate of recovery. The researchers believe this approach may reveal new targets for adjunctive therapies. The researchers aim to recruit 240 people, of all ages, who have been diagnosed with symptomatic malaria at selected hospitals in London. Blood samples, urine samples, and clinical information will be collected over the 14 days following malaria diagnosis.

Official title: Search for Correlates of Recovery in the Patient Transcriptome (SCRIPT) (Malaria) Study

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