Clinical Research Directory

Inclusion Criteria: * Adult patients (aged \>18 years) presenting in the emergency department * De novo acute hypoxemic respiratory failure (requiring oxygen flow rate of 5 liters per minute or more to maintain SpO2 of 90% or more) Exclusion Criteria: * Age \<18 years * Not admitted to the hospital * Postoperative acute respiratory failure (within one week from surgery) * Chronic hypoxemic respiratory failure (requiring long term oxygen therapy at home) * Hypercapnic respiratory failure * Transferred from another hospital or facility * Pregnant women * Admitted to the hospital purely to facilitate comfort care * Lack of informed consent