Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT05154864

Ultrafiltration in Pediatric Cardiac Surgery: An Observational Cohort Study

Sponsor: IWK Health Centre

View on ClinicalTrials.gov

Summary

Infants and children undergoing cardiac surgery with cardiopulmonary bypass (CPB) can experience systemic inflammation that prolongs post-operative recovery. Ultrafiltration is an intra-opreative technique that is hypothesized to extract circulating inflammatory mediators during the CPB time. There have been only a few small studies looking at a limited number of inflammatory marker profiles in this context. Our institution uses an innovative form of ultrafiltration "subzero-balance simple-modified ultrafiltration" (SBUF-SMUF) throughout the entire CPB time. SBUF-SMUF has been our standard of care for the last 5 years. This observational seeks to describe the clinical and immunologic outcomes of infants and children undergoing cardiac surgery with CBP and SBUF-SMUF.

Official title: The Optimal Ultrafiltration Protocol in Pediatric Cardiac Surgery: An Observational Cohort Study

Key Details

Gender

All

Age Range

Any - 15 Years

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2020-08-01

Completion Date

2021-06-30

Last Updated

2026-06-02

Healthy Volunteers

No

Interventions

PROCEDURE

SBUF-SMUF

Intra-operative continuous ultrafiltration

Locations (1)

IWK Health Centre

Halifax, Nova Scotia, Canada