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Ultrafiltration in Pediatric Cardiac Surgery: An Observational Cohort Study
Sponsor: IWK Health Centre
Summary
Infants and children undergoing cardiac surgery with cardiopulmonary bypass (CPB) can experience systemic inflammation that prolongs post-operative recovery. Ultrafiltration is an intra-opreative technique that is hypothesized to extract circulating inflammatory mediators during the CPB time. There have been only a few small studies looking at a limited number of inflammatory marker profiles in this context. Our institution uses an innovative form of ultrafiltration "subzero-balance simple-modified ultrafiltration" (SBUF-SMUF) throughout the entire CPB time. SBUF-SMUF has been our standard of care for the last 5 years. This observational seeks to describe the clinical and immunologic outcomes of infants and children undergoing cardiac surgery with CBP and SBUF-SMUF.
Official title: The Optimal Ultrafiltration Protocol in Pediatric Cardiac Surgery: An Observational Cohort Study
Key Details
Gender
All
Age Range
Any - 15 Years
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2020-08-01
Completion Date
2021-06-30
Last Updated
2026-06-02
Healthy Volunteers
No
Conditions
Interventions
SBUF-SMUF
Intra-operative continuous ultrafiltration
Locations (1)
IWK Health Centre
Halifax, Nova Scotia, Canada