Clinical Research Directory

Inclusion Criteria: * Patients with jaundice and an injury to the head of the pancreas recommended for EUS-guided tissue acquisition or staging * Patients with jaundice and distal CBD lesion suggestive of cholangiocarcinoma or Vater's ampulla carcinoma recommended for EUS-guided tissue acquisition or staging * Serum bilirubin level ≥ 3 mg / dl * Age ≥ 18 years old * Subject affiliated or beneficiary of a social security scheme. * Subject having been informed of this study and having given his no objection Exclusion Criteria: * Presence of altered anatomy due to previous gastric surgery (Billroth II or Roux-en-Y anastomosis) * Sphincterotomy performed previously, plastic biliary stent or metal stent placement * Percutaneous drainage of the bile ducts performed previously * Pregnant, breastfeeding or parturient woman * Protected patients: Adults under guardianship, curatorship or other legal protection, deprived of their liberty by judicial or administrative decision; hospitalized without consent.