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RECRUITING
NCT05155501
NA

Clinical Trial of Approaches to Prostate Cancer Surgery

Sponsor: Weill Medical College of Cornell University

View on ClinicalTrials.gov

Summary

This is a prospective, randomized controlled trial to compare cancer control and health-related quality of life following pelvic fascia-sparing radical prostatectomy versus standard radical prostatectomy. The investigators hypothesize that pelvic fascia-sparing radical prostatectomy will have similar cancer control (primary outcome) and sexual function outcomes; and significantly better urinary function, penile shortening/deformity and inguinal hernia risks as compared to radical prostatectomy.

Official title: Clinical TrIAL of Approaches to Prostate cAncer suRgery

Key Details

Gender

MALE

Age Range

40 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

600

Start Date

2023-05-15

Completion Date

2026-12

Last Updated

2025-05-20

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Robot-assisted radical prostatectomy (RP)

The conventional approach to prostate cancer surgery

PROCEDURE

Pelvic fascia-sparing robot-assisted radical prostatectomy (PFS-RP)

A novel, posterior approach to radical prostatectomy that preserves the dorsal vascular complex, nerves and fascial support structures that overlie the anterior prostate.

Locations (5)

Georgetown University

Washington D.C., District of Columbia, United States

Northwestern University

Chicago, Illinois, United States

Johns Hopkins University

Baltimore, Maryland, United States

NewYork-Presbyterian Queens

Flushing, New York, United States

Weill Cornell Medicine

New York, New York, United States