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Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
Sponsor: Natalie Lockney
Summary
This is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.
Official title: Phase I/II Trial of Gabapentin Plus Ketamine for Prevention and Treatment of Acute and Chronic Pain in Locally Advanced Head and Neck Cancer Patients Undergoing Primary or Adjuvant Chemoradiation
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2022-01-24
Completion Date
2026-12-31
Last Updated
2024-10-21
Healthy Volunteers
No
Interventions
Gabapentin
Taken by mouth 3 times per day
Ketamine
Administered intranasally 3 times per day
Locations (1)
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States