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Changes in Cognition and Psychiatric Disorder Symptoms During Cannabis Abstinence Using a Novel Discordant Twin Design
Sponsor: University of Colorado, Denver
Summary
This study will test whether 42 days of cannabis abstinence, compared to continued cannabis use, is associated with improvements in cognition and psychiatric disorder symptoms. Identical twins, who are concordant on cannabis use, will be experimentally-manipulated to be discordant for 42 days. Each twin, within a twin pair, will be randomly assigned to either the contingency management condition, incentive-based protocol to promote cannabis abstinence, or control condition, no changes in cannabis use requested.
Key Details
Gender
All
Age Range
31 Years - 47 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2023-05-05
Completion Date
2026-04-01
Last Updated
2026-02-12
Healthy Volunteers
Yes
Conditions
Interventions
Contingency management
Participants will be paid to abstain from cannabis use.
Locations (1)
Jessica M Ross
Aurora, Colorado, United States