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Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia
Sponsor: Northwestern University
Summary
This study uses magnetic resonance imaging to determine whether 3 weeks of repeated exposure to Acute Intermittent Hypoxia can improve brain blood flow or blood flow regulation in healthy adults.
Key Details
Gender
All
Age Range
21 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
33
Start Date
2022-05-03
Completion Date
2024-04-05
Last Updated
2026-07-20
Healthy Volunteers
Yes
Conditions
Interventions
Acute Intermittent Hypoxia
Participants will wear a non-rebreathing face mask and alternate between breathing 9% O2 gas mixture for up to 1 minute, or until the target SpO2 of 85 percent is reached, and normal room air (21 percent O2) until 2 minutes are complete. This cycle will be repeated 15 times, resulting in a 30-minute protocol.
Sham Acute Intermittent Hypoxia
Participants will wear a non-rebreathing face mask and breathe normal air (21 percent O2) for 30-minutes.
Locations (1)
Northwestern University
Chicago, Illinois, United States