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POHCA Resuscitation: Evaluation of IM Epinephrine
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Summary
This is a pragmatic, two-arm, open-label, prospective stepped-wedge cluster quasi randomized control trial (SW-CRCT) looking to evaluate early intramuscular (IM) epinephrine in the management of pediatric out-of-hospital cardiac arrest (POHCA).
Official title: Pediatric Out-of-Hospital Cardiac Arrest Resuscitation: Evaluation of IM Epinephrine (The PRIME Trial)
Key Details
Gender
All
Age Range
1 Day - 17 Years
Study Type
INTERVENTIONAL
Enrollment
284
Start Date
2024-01-08
Completion Date
2029-01
Last Updated
2025-03-11
Healthy Volunteers
No
Conditions
Interventions
Epinephrine Injection
Epinephrine administered via sterile epinephrine injection USP, by 0.3mg or 0.5mg epinephrine auto-injector(s) and/or pre-filled syringe (exact dose).
Locations (1)
Children's Hospital - London Health Sciences Centre
London, Ontario, Canada