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Investigation of Specific Biomarkers in Patients With Atrial Fibrillation Who Undergo Interventional Treatment
Sponsor: National Medical Research Center for Therapy and Preventive Medicine
Summary
The two main mechanisms for atrial fibrillation (AF) recurrence after cryoablation include Pulmonary vein (PV) reconnection and the presence of non-PV associated arrhythmic focuses. The aim of this study is to reveal the specific biomarkers by antibody microarrays.
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2021-01-01
Completion Date
2028-01-31
Last Updated
2026-08-26
Healthy Volunteers
Not specified
Conditions
Interventions
Proteomic analysis by antibody microarrays
Proteomic analysis by antibody microarrays can be used to identify novel biomarkers and to investigate various signaling pathways including protein phosphorylation and protein-protein interactions. Microchips are manufactured as a matrix of a number of immobilized antibodies covalently bound to the glass, membrane, or gel surfaces. Microchips are used for serum proteomic studies in patients with cardiovascular diseases and cancer
Locations (1)
National Research Center for Preventive Medicine
Moscow, Russia