Clinical Research Directory

PLWH. The eligibility criteria for PLWH include: 1\) at least 18 years of age; 2) a confirmed diagnosis of HIV or AIDS; 3) with a detectable viral load (i.e., viral load≥50 copies/mL) or a viral round during the past year (a confirmed detectable viral load following a suppression); 4) willing to refer or give permission for us to contact one of their adult family member (either of origin or of choice) to participate (but the decision to participate will solely reside in the family member); 5) willing to provide a hair sample for test of hair cortisol and ARV hair concentration; 6) willing to consent the retrieval of their past and recent CD4 count and viral load from their medical charts; and 7) willing to be randomized to intervention condition at different time point in the stepped wedge trial. The exclusion criteria for PLWH include 1. mental or physical inability to respond to assessment questions or to participate in intervention; 2. currently incarcerated or institutionalized for drug use or commercial sex; 3. participating in other intervention activities during the current study period; and 4. plan to permanently relocate outside of the province within a year. Physical and developmental inability will be screened by the local research team in consultation with physicians at the participating clinics. Family members. The eligibility criteria for family members include 1. at least 18 years of age; 2. either family member of origin or family member of choice who provide emotional and other social support to study PLWH; 3. have been referred by case PLWH to participate in the study; and 4. willing to be randomized (along with study PLWH) to intervention condition. The exclusion criteria for family members will be the same as PLWH. Note: An HIV-infected family member will be eligible to participate. The decision of the family member to or not to participate will not affect the eligibility of PLWH to participate. Based on our experience working with PLWH in Guangxi, we anticipate that at least 80% of the referred family members will participate. With appropriate consent, we will collect brief information (e.g., key demographic characteristics and treatment profiles) on those PLWH who either cannot identify a family member (of origin or of choice) or her/his family member refuses to participate for potential secondary analysis to inform the refinement and scale-up of the proposed intervention in the future. Health care providers. The eligibility criteria for health care providers include: 1. at least 18 years of age; 2. provides health care services at one of the participating HIV clinics; and 3. has regular contact with HIV-infected patients. The exclusion criteria for health care providers include 1\) a plan to permanently relocate outside of the province within a year.