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RECRUITING
NCT05175248
NA

Nutritional Intervention for Endometriosis

Sponsor: Physicians Committee for Responsible Medicine

View on ClinicalTrials.gov

Summary

In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome composition, and hormonal changes.

Official title: A Randomized Controlled Trial of a Nutritional Intervention for Endometriosis

Key Details

Gender

FEMALE

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2022-03-02

Completion Date

2026-12

Last Updated

2026-01-02

Healthy Volunteers

No

Conditions

Interventions

BEHAVIORAL

Plant-based Intervention Group

Participants in the intervention group will be instructed in ways to adopt a plant-based diet, use appropriate methods of food preparation, and make meals enjoyable and appetizing. The plant-based diet primarily emphasizes whole grains, vegetables, beans and legumes, and fruits. Animal products and added oils will be proscribed and the use of ultra-processed foods, sugar, and sugar-sweetened beverages will be discouraged. Fat intake will be limited to 20-30 g/day.

Locations (1)

Physicians Committee for Responsible Medicine

Washington D.C., District of Columbia, United States