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Nutritional Intervention for Endometriosis
Sponsor: Physicians Committee for Responsible Medicine
Summary
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks. Participants in both groups will be asked to make no changes to their exercise patterns for the study period. Changes in pain, quality of life, and inflammatory biomarkers from baseline to final will be the primary outcomes. Secondary outcomes will include changes in body weight, blood lipids, gut microbiome composition, and hormonal changes.
Official title: A Randomized Controlled Trial of a Nutritional Intervention for Endometriosis
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2022-03-02
Completion Date
2026-12
Last Updated
2026-01-02
Healthy Volunteers
No
Conditions
Interventions
Plant-based Intervention Group
Participants in the intervention group will be instructed in ways to adopt a plant-based diet, use appropriate methods of food preparation, and make meals enjoyable and appetizing. The plant-based diet primarily emphasizes whole grains, vegetables, beans and legumes, and fruits. Animal products and added oils will be proscribed and the use of ultra-processed foods, sugar, and sugar-sweetened beverages will be discouraged. Fat intake will be limited to 20-30 g/day.
Locations (1)
Physicians Committee for Responsible Medicine
Washington D.C., District of Columbia, United States