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Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome
Sponsor: Vastra Gotaland Region
Summary
This study proposes to conduct the switch from ticagrelor to prasugrel in an organized stepwise manner, to allow for the evaluation of the relative efficacy of prasugrel versus ticagrelor using a stepped-wedge cluster randomized trial design.
Official title: Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome-a Stepped Wedge Cluster Randomized Evaluation in the SWEDEHEART-registry
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
17095
Start Date
2022-02-01
Completion Date
2025-08-31
Last Updated
2026-07-08
Healthy Volunteers
No
Conditions
Interventions
Prasugrel 10 mg p.o
Prasugrel 10 mg once daily p.o. Patient \>75 years of age or \<60 kg will receive 5 mg prasugrel OD.
Ticagrelor 90 mg
Ticagrelor 90 mg twice daily p.o.
Locations (1)
Dep. Cardiology, Skånes universitetssjukhus
Lund, Sweden