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Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome
Sponsor: Northwestern University
Summary
This study seeks to identify defects in immune activation or regulation that may affect a subset of patients with CP/CPPS. This subset appears to have a reduced ability to mount a regulatory immune response, while simultaneously eliciting an exaggerated activated immune response. The defects that we demonstrate appear to be linked to altered methylation of genes involved in both immune regulation and immune activation. The aims of this study will provide definitive evidence of a role for epigenetic changes in immune cells in patients with CP/CPPS.
Key Details
Gender
MALE
Age Range
21 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2021-10-11
Completion Date
2025-12-11
Last Updated
2024-12-18
Healthy Volunteers
Not specified
Conditions
Locations (1)
Northwestern Memorial Hospital
Chicago, Illinois, United States